The regular intake of Zoloft brings an end to any depression symptoms before the patient thinks of doing any harm to themselves. zoloft without rx Anxiety and depression symptoms don't seem to be dangerous during the early stages, however with time the symptoms become so grave that they may pose a risk to your life. The Sertraline is the anti-depressant making Zoloft a Selective Serotonin Reuptake Inhibitor (SSRI). The Zoloft oral medicine contains the chemical Sertraline in large number.